Thursday 7 February 2019

Drynaria fortunei - Gu-Sui-Bu - Benefits and Properties

Drynaria fortunei, commonly known in China as Gu-Sui-Bu, is a species of basket fern of the family Polypodiaceae. The plant is native to Eastern Asia, including eastern China. Preparations from the roots of Drynaria have been used in traditional Asian medicine for aiding in the healing of bone fractures and for treating rheumatoid arthritis. 
Excessive bone loss, known as osteopenia or osteoporosis, is characterised by an imbalance between the bone-destroying cells, osteoclasts, and bone-building cells, osteoblasts. Human and animal data showed that Drynaria inhibiting osteoclast function without entirely halting it, as bisphosphonate drugs (alendronate, risedronate, ibandronate etc.) do. It stimulates osteoblasts to produce more healthy bone tissue. In addition, Drynaria attracts mesenchymal stem cells to accelerate the damaged bone repair. Drynaria has been shown to provide anti-osteoporotic effects in female mammals following the loss of ovaries and in animals with experimental osteoporosis induced by rheumatoid arthritis.

In addition, Drynaria extract exhibits an anti-inflammatory activity, protect the kidney from renal failure and possess an anti-tumour activity against multiple myeloma. 

Potential indications for the use of Drynaria in humans include:

Osteopenia
Osteoporosis
Poor dental health
Periodontal gum disease
Prevention of bone loss in postmenopausal women and people with rheumatoid arthritis, diabetes and those who take steroids (prednisone) on a long-term basis
Inflammation and pain management in patients with rheumatoid arthritis and osteoarthritis
Adjunct therapy of multiple myeloma
Adjunct treatment of renal insufficiency

Potential side effects:

Dizziness and lightheadedness
Mild nausea
Gastrointestinal discomfort

Potential drug interactions:

Bisphosphonates (alendronate, risedronate, ibandronate etc)
Calcitonin
Denosumab (prolia)
Teriparatide (Forteo)
Coumadin

Contraindications:

Pregnancy
Lactation
Chronic anticoagulation therapy

Complementary natural products:

Biotin
Calcium Lactate
Indian Thorny Bamboo
Magnesium Malate
Strontium Citrate
Taurine
Vitamin D

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